The newly developed antibacterial quaternary ammonium silane increases the
resistance of dentin collagen to degradation by inhibiting endogenous matrix metalloproteinases and
cysteine cathepsins. The quaternary ammonium silane cavity disinfectant is promising for use as a
protease inhibitor to improve durability of resin-dentin bonds.

The newly developed antibacterial quaternary ammonium silane increases the
resistance of dentin collagen to degradation by inhibiting endogenous matrix metalloproteinases and
cysteine cathepsins. The quaternary ammonium silane cavity disinfectant is promising for use as a
protease inhibitor to improve durability of resin-dentin bonds.